It seems like my favorite cartoon from MTV this side of Daria, Aeon Flux, will be headed to the big screen in a live-action film directed by Karyn Kusama. I would much rather have an animated film, because the world that Peter Chung was so trippy and cool, but Kusama did a great job of turning Michelle Rodriguez into a boxer.
Here's a great Aeon Flux episode guide
Aeon Flux creator Peter Chung takes about the moral vacuum Aeon's was in. Also, a chat transcript with him, discussing anime.
Watch an amazing reel of Peter Chung's work
Buy Aeon Flux on VHS or DVD